In an experiment utilizing azoxymethane/dextran sulfate sodium-induced inflammation-associated colorectal cancer mice, which were divided into a control group, a model group, and a ginsenoside Rg-3 group, each consisting of 16 mice, it was concluded that low expression of the Notch1 signaling pathway is related to enhanced angiogenesis, thereby inhibiting the progression of azoxymethane/dextran sulfate sodium-induced colorectal cancer. The gene discussed is NOTCH1; the disease is colorectal cancer.