Given the increased permeability of the microvascular beds of affected organs composed of endothelial cells, such as the kidney has been reported in HFRS patients, and coagulation disorder can also be found in such patients, the relationship between TM and various related conventional parameters, including PLT, Cr, urea, UA, APTT, PT, Fib, WBC, and CRP, was evaluated. This evidence concerns the gene F2 and blood coagulation disease.