The median methylation levels of MLH1, MGMT, p16INK4a/+68, and p16INK4a/+235 in matching mucosa of colon cancer patients (non-cancerous mucosa) were 1.2% (range 0.6–6.2), 3.0% (range 0.6–10.4), 2.8% (range 1.2–23.6), and 3.6% (range 1.9–7.6), respectively. The gene discussed is MGMT; the disease is colonic neoplasm.