According to the 2023 International Evidence-Based Guidelines for the Evaluation and Management of PCOS in adults, diagnosis requires the presence of at least two of the following criteria after ruling out differential diagnoses: clinical or biochemical hyperandrogenism, ovulatory dysfunction, and polycystic ovary morphology confirmed by gynecologic ultrasonography or elevated serum Anti-Mullerian hormone levels (2). The gene discussed is AMH; the disease is polycystic ovary syndrome.