Globally, poor ART adherence, HIV-advanced disease, low CD4 cell count, absence of cotrimoxazole and Isoniazid preventive therapies are risks recognised factors for death in HIV–TB coinfected patients.43,44,45 Although the univariate analysis showed a higher frequency of deaths among PLHIV aged over 45 years old (42.1%), those with extra-pulmonary TB (35.3%) and PLHIV with a concomitant opportunistic infection (42.3%), these associations were not significant in the bivariate analysis (Table 3), possibly because of the small sample size. This evidence concerns the gene CD4 and Opportunistic infection.