Additionally, SF3B6 expression exhibited negative correlations with tumor metabolism-related pathways, including alcoholic liver disease, the PPAR signaling pathway, the AMPK signaling pathway, primary bile acid synthesis, adipokine biosynthesis, valine/isoleucine/leucine degradation, arginine biosynthesis, mineral absorption, glycine/serine/threonine metabolism, peroxisome metabolism, cGMP-PKG signaling pathway, and fatty acid degradation (Figure 9A). Here, PPARA is linked to alcoholic liver diseases.