S V Demyanenko et al. constructed a photothrombotic stroke (PTS) model using rats, and they found that the expression of HAT1 and P300/CBP-associated factor (PCAF) was upregulated in the ischemic semi-dark band of the rat cerebral cortex at 4–24 h after PTS, and that HAT1 being localized in astrocytes (Demyanenko and Uzdensky, 2019). This evidence concerns the gene HAT1 and stroke disorder.