TEAD1 and myocarditis: ICI-related myocarditis reduces Mst1 kinase activity and activates TAZ, which acts as a co-activator of RORγt to promote Th17 cell differentiation and inhibit Treg cell development, TEA domain transcription factor 1 (TEAD1) suppresses TH17 differentiation and promotes Treg cell development by inhibiting the function of TAZ (117).