The PPI network identified that ESRRG was significantly related to 20 genes, including PPARGC1A, PPARGC1B, MED1, CREBCF and so on (Figure 3A), 6 of which were confirmed to be positively correlated with ESRRG expression by the XenaShiny TCGA Association Analysis module for single cancer (Figures 3B-G). The gene discussed is MED1; the disease is cancer.