Highly expressed in PC, class I HDAC expression in prostate tissue; HDAC1 and HDAC2 positively correlate with Gleason score (HDAC1, p = 0.006; HDAC2, p = 0.047; HDAC3, p = 0.584) and Ki-67 proliferative index. Here, HDAC1 is linked to pachyonychia congenita.