These findings were replicated using matched blood, skeletal tissue and adipose tissue from nine monozygotic twin pairs discordant for T2D, with correlations found between blood and adipose tissue for SOCS3 and SREBF1 sites (Regression coefficient = 0.31 and 0.40, p = 0.010 and 0.052, n = 28) (Dayeh et al., 2016). Here, SREBF1 is linked to type 2 diabetes mellitus.