The reduced prolactin levels observed in this study may be due to the lower TSH levels in the menorrhagic group, as previous research has established a connection between TSH and prolactin levels.35 The lack of significant association between prolactin levels and the likelihood of experiencing menorrhagia implies that clinicians should not rely on prolactin measurements alone when assessing patients with heavy menstrual bleeding. This evidence concerns the gene PRL and Menorrhagia.