PLOD1 and Menorrhagia: Hormonal imbalances are responsible for 80% of cases of abnormal uterine bleeding.6 Deficiency in thyroid hormones and irregularities in thyroid stimulating hormone (TSH) can impact ovarian function via multiple mechanisms, potentially altering follicle stimulating hormone (FSH) and luteinising hormone (LH), and affecting the metabolism of peripheral steroid hormones, prolactin, and sex hormone-binding globulin.7 Despite the known interaction between thyroid function and menstrual disorders, data specifically linking thyroid hormones with menorrhagia remain limited.