IFNGR1 and neoplasm: Synthesis of glycosphingolipid, a phospholipid, is critical for successful immune escape in KRAS mutation-driven tumors: the level of glycosphingolipid synthesis correlates with the amount of interferon gamma receptor 1 (IFNGR1) on the surface of cancer cells, and blocking glycosphingolipid synthesis leads to an increase in IFNGR1, making the tumor cells more sensitive to immune responses (Soula et al., 2024).