Further studies found that YTHDF3 promoted the translation of epidermal growth factor receptor (EGFR), gap junction protein alpha 1 (GJA1), and ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5) in an m6A-dependent manner, which ultimately led to an increase in breast cancer brain metastasis (Chang et al., 2020) (Figure 7). This evidence concerns the gene YTHDF3 and breast cancer.