LCN2 and neoplasm: Previous work from multiple laboratories has demonstrated that LCN2 promotes invasion and metastasis in multiple tumor types (Basu et al., 2018; Ding et al., 2015; Guo et al., 2014; Leng et al., 2009; Miyamoto et al., 2016; Oren et al., 2016; Yang et al., 2009).