Changes in cholinergic function during aging and AD have been widely documented using various cholinergic parameters, such as high‐affinity choline uptake transporter (CHT1), vesicular ACh transporter (VAChT), ACh esterase (AChE), muscarinic and nicotinic ACh receptors, ACh quantity, release, and neuronal density (Apelt et al. 2002; Liu et al. 2022). Here, SLC5A7 is linked to Alzheimer disease.