Variants in QRICH1 have been associated with developmental delay, neurodevelopmental disorders, renal agenesis, and congenital heart disease (Baruch et al. 2021; San Agustin et al. 2016; Li et al. 2015), underscoring its importance in maintaining the normal structure of tissues with high protein synthesis demands. This evidence concerns the gene QRICH1 and renal agenesis.