These results were consistent with those from microarray analysis, and RT-qPCR confirmed that these 4 genes were highly expressed in a TGF-β1-induced HFL-1 cell lung fibrosis model.cd19, a B cell-specific member of the immunoglobulin superfamily, is expressed by pre-B cells that have undergone heavy-chain rearrangement and continue to be expressed until early plasma cell differentiation.[17,18] This 95-kDa type I membrane glycoprotein[19] is broadly distributed on the surface of B cells. The gene discussed is CD19; the disease is pulmonary fibrosis.