Under physiological conditions, slamf7 is expressed at low levels in various immune cell populations, including partially activated T and B cell subsets, dendritic cells, monocytes/macrophages, and plasma cells.[41,42] Previous research has indicated that slamf7 expression is markedly elevated in B cells from rheumatoid arthritis-associated interstitial lung disease patients compared to those with RA alone. This evidence concerns the gene SLAMF7 and interstitial lung disease.