IL10RB and male reproductive organ cancer: IL-10 may lead to chronic inflammation by inhibiting the proliferation of CD4+ and CD8+ T cells,[23] potentially resulting in the infection of latent pathogens such as Chlamydia trachomatis and viruses within the prostate or reproductive tract.[24,25] MR analysis indicates no causal relationship between IL-10, IL-10RB, and prostatitis, while IL-10RA is identified as a risk factor for prostatitis.