The IVW analysis results for CCL23 (IVWCCL23: OR = 0.949, 95% CI: 0.906–0.993, P = .025), IL-5 (IVWIL-5: OR = 0.938, 95% CI: 0.890–0.988, P = .016), and TRANCE (IVWTRANCE: OR = 0.947, 95% CI: 0.905–0.992, P = .021) indicated a decrease in their expression levels in the plasma of prostatitis patients. The gene discussed is TNFSF11; the disease is urogenital neoplasm.