Dysregulated DPP8/9 levels and activities have been linked to tumour development, organ fibrosis, the initiation of pyroptosis, and inflammatory responses (Okondo et al, 2017; Tang et al, 2017; Johnson et al, 2018; Huang et al, 2021; Zhang et al, 2021; Harapas et al, 2022). The gene discussed is DPP8; the disease is neoplasm.