AR and neoplasm: AR axis alterations were significantly more likely to be identified in non-Hispanic White samples derived from primary (707 of 1521 [46.5%] vs 295 of 838 [35.2%]; P < .001) and metastatic (388 of 695 [55.8%] vs 126 of 316 [39.9%]; P < .001) tumor tissue; however, no differences were uncovered in plasma samples (334 of 1015 [32.9%] vs 195 of 629 [31.0%]; P = .61).