We found that serum sclerostin levels in all of our T1DM patients didn’t correlate with gender, which was in accordance with a previous Japanese study [15], while previous Italian [16] and Greek [17] pediatric studies contrasted with our findings, where they found that gender influenced sclerostin levels, with higher levels observed in male T1DM patients compared to females. This evidence concerns the gene SOST and type 1 diabetes mellitus.