IFNB1 and eye infection: WT mice infected with 2 × 105 PFU/eye of LAT(+) virus: 15 of 18 (83%) mice survived ocular infection, while 23 of 44 (52%) of IFNβ-/- mice infected with the same virus survived ocular infection, and these differences were statistically significant [Table 1; P = 0.03, 2 × 105, LAT(+)].