Furthermore, 23 of 44 (52%) of IFNβ-/- mice infected with 2 × 105 PFU/eye of LAT(+) virus survived ocular infection, while 20 of 49 (41%) of mice infected with LAT(-) virus survived infection (Table 1; 2 × 105, P = 0.34). The gene discussed is IFNB1; the disease is eye infection.