IFNB1 and eye infection: In WT mice infected with 1 × 105 PFU/eye of LAT(+) virus, six of seven (85%) mice survived ocular infection, while 16 of 29 (55%) of IFNβ-/- mice infected with the same virus survived ocular infection, and these differences were statistically significant [Table 1; P < 0.05, 1 × 105, LAT(+)].