SSTR5 and paraganglioma: In particular: [68Ga]Ga-DOTA-TATE has an affinity for SSTR2 (highly expressed in NETs); [68Ga]Ga-DOTA-NOC has a good affinity for SSTR3 and SSTR5, while [68Ga]Ga-DOTA-TOC has an affinity for tumors that overexpress somatostatin receptors SSTR2 and SSTR5 [6, 7], such as low-grade gastroenteropancreatic neuroendocrine tumors (GEP-NET), pheochromocytomas, and paragangliomas [1].