Recent joint guidelines published by associations such as American Urological Association indicate the corresponding PSA threshold concentrations for PCa prognosis, where men with PSA concentrations of <10 μg/l should be categorized as very low or low risk, men with PSA concentrations of 10 to <20 μg/l should be considered to be at recurrence risk moderate, and men with PSA concentrations of ≥20 μg/l should be considered at high risk for recurrence [34]. The gene discussed is KLK3; the disease is posterior cortical atrophy.