Baicalein inhibits the expression and activity of P-glycoprotein resulting in the accumulation of intracellular rhodamine 123.Baicalein down-regulates BDLNR in poor cervical cancer in vivo which is bound to Y-box binding protein 1 (YB-1), recruited YBX1 to PIK3CA promoter, activated PIK3CA expression and PI3K/Akt pathway. This evidence concerns the gene AKT1 and cervical cancer.