Thereby, we could partially confirm our microarray data by showing upregulation of S100A8 and S100A9 in T cells and also in human samples using qPCR - both S100A8 and S100A9 were found significantly upregulated on CD4 and CD8 T cells isolated from blood PBMCs of HCC patients. Here, S100A9 is linked to hepatocellular carcinoma.