In vitro and in vivo downregulation of Keap1 and upregulation of Nrf2 stimulated the expression of superoxide dismutase 2 (SOD2), an antioxidant protein, confirming the regulatory importance of miR-200a-3p to facilitate kidney repair, potentially reducing the risk of CKD development (Cao et al., 2020). The gene discussed is SOD2; the disease is chronic kidney disease.