CAIS is the inactivation mutation of the AR gene, resulting in the absolute insensitivity of embryonic tissue to androgens, differentiation of Wolff tube and urogenital sinus in such a way that causes male genital duct obstruction, and the restriction of testicular descent into cryptorchidism, which can be located in any part of the descending testicular pathway (e.g., abdominal pelvis, inguinal canal, and labia major) (13). The gene discussed is AR; the disease is complete androgen insensitivity syndrome.