IL6 and coronary artery disorder: The diagnostic efficacy of IL-6 and TMAO for CAD was evaluated using ROC curves.It was observed that the cut-off value of IL-6, set at 45.17, demonstrated thestrongest diagnostic performance for CAD (sensitivity 69.6%, specificity 73.1%,area under the curve 0.770, 95% CI: 0.662–0.879, p< 0.001).Similarly, TMAO exhibited the highest diagnostic value for CAD (sensitivity65.2%, specificity 76.9%, area under the curve 0.689, 95% CI: 0.564–0.814,p = 0.008) at a cut-off of 12.44.