Levels of free fatty acids, cardiolipin and phosphatidylinositol were decreased, and ceramide and diacylglycerol were used as combined tissue markers to distinguish adenocarcinoma from squamous cell carcinoma, PC(38:6) and Cer G3 (d18:1/22:0) were used as potential markers to distinguish lung cancer from healthy tissue. The gene discussed is CBLN1; the disease is squamous cell carcinoma.