SERPING1 and hereditary angioedema: 60/75 HAE-C1INH patients had been treated only with Danazol as long-term prophylaxis, and this number reflects the fact that, for most of the period under consideration, specific prophylactic medications such as i.v. or s.c. Plasma-derived C1INH, Lanadelumab, and Berotralstat were not yet available.