Concurrently, KEGG analysis (Figure 3C) revealed pathways related to angiogenesis and vascular functions (platelet activation; relaxin signaling pathway), structural reorganization (ECM receptor interaction; protein digestion and absorption), regulation of cellular proliferation (PI3K‐Akt signaling pathway; proteoglycans in cancer), and inflammation‐inducing pathological conditions (AGE‐RAGE signaling pathway in diabetic complications; diabetic cardiomyopathy; amoebiasis). The gene discussed is AKT1; the disease is diabetic cardiomyopathy.