BCL2 and cancer: Adenoviruses have recently been used as effective transport systems for delivering drugs to suppress tumors.[62] Falanga et al.[66] reported that oncolytic adenoviral vectors (OAds) can target tumor cells and deliver a PNA quadruplex, able to target oncogene promotors and reduce the expression of anti‐apoptotic Bcl‐2, a protein found in various cancers.[67] To improve the attraction between the anionic surface of OAd and PNA, the PNA backbone was modified by adding positively charged lysines (from 1 to 6 K), called PNA6K.