Notably, the observed connections between miR-17-5p, miR-106a-5p, and DNMT1 suggest that these miRNAs may influence the epigenetic regulation of DNA methylation, potentially altering the expression of other components of the regulatory network—including lncRNAs and EMT-related genes—and thereby contributing to the complex landscape of tumor progression. The gene discussed is DNMT1; the disease is neoplasm.