CLOCK and cancer: Moreover, of the 37 genes that lost rhythmicity in response to cancer that were identified as direct FoxP1 targets, 24 (65%) were also identified via ChIP-seq as direct targets bound by BMAL:CLOCK in skeletal muscle (Table S2).33 This close proximity in FOXP1 and BMAL1 binding at certain genomic loci could thus lead to co-regulation of these genes, which warrants further investigations.