After multivariate regression analyses, ApoE ε4 was not associated with the risk of PSCI across all models, both at 3 months (OR = 0.80, p = 0.5587 in Model I; OR = 0.71, p = 0.3756 in Model II; OR = 0.79, p = 0.6181 in Model III; Supplementary Table 3) and 12 months (OR = 0.41, p = 0.2692 in Model I; OR = 0.35, p = 0.2678 in Model II; OR = 0.56, p = 0.5682 in Model III; Supplementary Table 4) post stroke. This evidence concerns the gene APOE and stroke disorder.