Interestingly, MUC1, previously reported to stabilize MYC and promote NOTCH pathway activation, thereby promoting cancer.[38] PKCζ phosphorylates MYC at the Ser373 site, promoting its degradation.[72] We found that MUC1 constrains PKCζ activity by enhancing PP2A activation, which may also increase MYC stability. The gene discussed is PTPA; the disease is cancer.