Mucin1 (MUC1) is a type I transmembrane glycoprotein that forms a mucus barrier under physiological conditions, shielding epithelial cells from environmental insults.[21, 22, 23] However, MUC1 is overexpressed in tumor cells, contributing to malignant transformation and tumorigenesis,[24, 25, 26, 27] promoting tumor metastasis,[28] and facilitating drug resistance and immune escape.[29, 30, 31, 32] Our previous studies have revealed that MUC1 plays a crucial role in regulating CSCs. The gene discussed is MUC1; the disease is neoplasm.