CD7 and brain neoplasm: Multi‐omics analyses have shown that after CD7+ T cell exhaustion, regenerated CD7− T cells exhibit enhanced immune functionality compared to normal T cells, resembling immune characteristics observed in autoimmune diseases.[137, 138] In pediatric patients with brain tumors receiving CAR‐T therapy, scRNA‐seq analysis of peripheral blood T cells revealed post‐treatment infiltration into the cerebrospinal fluid, accompanied by clonal expansion, indicating a response of the endogenous immune system to CAR‐T cells.[139]