A similar phenotype including left–right defects, hydrocephalus, and perinatal mortality is observed in mice deficient in genes regulated by Foxj1 that are commonly deficient in PCD, such as the murine orthologues of DNAH5, DNAI1, DNAAF5, CCDC39, and CCDC40 [35–40]. The gene discussed is FOXJ1; the disease is Hydrocephalus.