Additionally, the HR status (positive vs negative) (OR 0.424, 95% CI 0.183–0.979) tumor grade (3 vs 1–2) (OR 2.661, 95% CI 1.134–6.242) and Ki-67 (≥ 40% vs < 40%) (OR 0.330, 95% CI 0.145–0.751), were also identified as significant independent factors that influence the risk of relapse (Table 3). Here, MKI67 is linked to neoplasm.