In this study, in a single experiment, we were able to recapitulate IDO1 expression in BrCa25 and uncovered high expression of TDO2, AADAT/KAT-II, KYNU, CYP1B1 EGF, KLK3, MMPs, MUC1,PLAUR and TP53 suggesting their potential roles in BrCa pathology and poor prognosis26,29. This evidence concerns the gene EGF and invasive breast carcinoma.