The results of non-genetic analyses broadly aligns with results from the UK Biobank cohort in terms of (i) prevalence estimates of depression and anxiety, (ii) robust univariate associations between CRP and depression and anxiety, which were generally no longer statistically significant when controlling for covariates, and (iii) stronger univariate associations for CRP and depression when compared to anxiety [37]. Here, CRP is linked to major depressive disorder.