In order to generate a fully autologous vToC, with tumor‐infiltrating immune cells, we processed the surgical sample of patient #14 by combining the EC isolation protocol from healthy tissue as described above (Figure 2A) with the isolation protocol of cancer cells, CAFs and CD8+ TILs from tumor tissue, which we previously described.[63] The four autologous cell populations were cultured in appropriate media and supports for few weeks (see Experimental Section) before seeding in the vToC. This evidence concerns the gene CD8A and cancer.