described [85] the relationship between Mtb‐specific CD4+ T cell PD‐1 expression and human TB bacterial load, using peripheral blood samples from LTBI and TB patients, and found significantly higher PD‐1 expression levels on Th1 + CD4 T cells in smear‐positive TB patients compared to smear‐negative TB and LTBI patients, with levels decreasing after completing anti‐TB treatment. The gene discussed is CD4; the disease is tuberculosis.