TNF and non-small cell lung carcinoma: Among the NSCLC patients, we found that 14/28 (50%) of NSCLC BM patients showed reduced overall cytokine production (Supplemental Fig. 7b), while the other half of the patients could be divided into a group of predominantly TNFa and IFNy producers (9/14), and a second subgroup (5/14) of patients with polycytokine production.