MYC and neoplasm: Moreover, compared to the oe-NCL + oe-NC + oe-NC group, the oe-NCL + oe-MYC + oe-NC group showed decreased tumor cell proliferation, increased apoptosis (Fig. 7G-H, Figure S7A-B), significantly increased permeability (Fig. 7I, Figure S7C), and a notable decrease in the invasive spread capacity of spheroids (Fig. 7J, Figure S7D).