TXNIP and neoplasm: Furthermore, when compared to the oe-NCL + oe-MYC + oe-NC group, the oe-NCL + oe-MYC + oe-TXNIP group exhibited enhanced tumor cell proliferation, reduced apoptosis (Fig. 7G-H, Figure S7A-B), significantly decreased permeability (Fig. 7I, Figure S7C), and a notable increase in the invasive spread capacity of spheroids (Fig. 7J, Figure S7D).