KAT5 and glioblastoma: Second, genes whose expression was preferentially induced in KAT5 KO cells were significantly enriched for neural developmental and GBM stem cell genes and transcription factors: including NPAS3, required for stemness of radial glial cells50, SOX9 and ID4, both with roles in maintaining GBM stem-like cells51,52 (Fig. 3b, c).