For KAT5on tumors, 521 superenhancer regions were identified that were associated with genes implicated in GBM mesenchymal cell states (e.g., BCL3, CD44, RGS16), GBM survival (SEC61G, VGF), neurogenesis/stemness (PBX1), and cell cycle (CDK6) (Supplementary Fig. 12g). Here, RGS16 is linked to glioblastoma.