RIPK1 and glaucoma: Also, RIPK1/RIPK3 inhibition or RIPK1/3 gene manipulation can prevent RGC loss in several models of glaucoma, such as ischemia/reperfusion, optic nerve crush, and glutamate excitotoxicity (Do et al, 2017; Liu et al, 2022; Kim et al, 2024; Tu et al, 2025).