CD8A and rectum adenocarcinoma: In colon adenocarcinoma, the somatic copy number alterations (SCNAs) of CCNA2 correlated with the infiltration levels of B cells, CD8+ T cells, and dendritic cells; in rectum adenocarcinoma, somatic copy number alteration (SCNA) of CCNA2 correlated with the infiltration levels of macrophages (Fig. 2B).